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AboutCommitment to the GH communityCommitment to the GH communityIndications & DosingAdultsChildren AdultsChildren DevicesPenPen presentationHow to use the Pen videoMiniQuickMiniQuick presentationHow to use the MiniQuick videoSupport and ServicesMaterialsVideosPatient Support and SavingsMaterialsVideosPatient Support and Savings
Prescribing InformationIndications Patient Site
The Pfizer Bridge Program®The Pfizer Bridge Program®Support for your GENOTROPIN patients throughout treatment

Our dedicated Patient Care Consultants (PCCs) are there to help support your patients. See some of the available Pfizer Bridge Program resources below.

Patient services
Benefit verification
Prior authorization assistance*
Appeals assistance*
Copay assistance†
Specialty pharmacy setup
Reauthorization and insurance changes

 

Benefit verification Copay assistance†
Prior authorization assistance* Specialty pharmacy setup
Appeals assistance* Reauthorization and insurance changes
Device training and patient resources

Device training and patient resources

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The GENOTROPIN Starter Kit Device Support Hotline
Initial in-home or virtual training    
The GENOTROPIN Starter Kit 
Initial in-home or virtual training
Device Support Hotline
ReferencesOnce a Patient Enrollment Form has been submitted, PCCs can work with your patient to review either the prior authorization process and/or the reason for the denial. Once a prior authorization and/or appeal is submitted by the HCP, they can follow up with the payer on behalf of the patient and track the process until a final outcome is determined.For eligible patients.
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PCCs are available at 1-800-645-1280
GENOTROPIN Copay Program
We are committed to helping with out-of-pocket costs for patients. That's why we've developed the GENOTROPIN Copay Program. See terms and conditions below.
ReferencesEligibility required. Annual savings up to $5,000. State and federal health care program beneficiaries not eligible even if they elect to be processed as an uninsured (cash-paying) patient. Terms and conditions apply. Please see full terms and conditions below. The copay program is not health insurance.ReferencesData based on Pfizer Bridge Program benefit verification for eligible patients as of Feb-Jul 2022. Excludes process terminated patients.Dependent on individual insurance plan restrictions. Additional requirements may apply.GENOTROPIN Copay Program Terms and Conditions
By using this copay card, you acknowledge that you currently meet the eligibility criteria and will comply with the terms and conditions described below:
Patients are not eligible to use this card if they are enrolled in a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veterans Affairs health care, or a state prescription drug assistance program. Patient must have private insurance. Offer is not valid for cash paying patients. Patients are responsible for as little as a $0 monthly copayment based upon program utilization. The value of this copay card is limited to a maximum of $5,000 per calendar year. This copay card is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plan or other private health or pharmacy benefit programs. You must deduct the value of this copay card from any reimbursement request submitted to your private insurance plan, either directly by you or on your behalf. You are responsible for reporting use of the copay card to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the copay card, as may be required. You should not use the copay card if your insurer or health plan prohibits use of manufacturer copay cards. This copay card is not valid where prohibited by law. Copay card cannot be combined with any other savings, free trial or similar offer for the specified prescription. Copay card will be accepted only at participating pharmacies. If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this offer. This copay card is not health insurance. Offer good only in the U.S. (excluding Puerto Rico, the U.S. Virgin Islands, and Guam). Copay card is limited to 1 per person during this offering period and is not transferable. A copay card may not be redeemed more than once per 30 days per patient. No other purchase is necessary. No membership fee. Data related to your redemption of the copay card may be collected, analyzed, and shared with Pfizer, for market research and other purposes related to assessing Pfizer’s programs. Data shared with Pfizer will be aggregated and deidentified; it will be combined with data related to other copay card redemptions and will not identify you. Pfizer reserves the right to rescind, revoke or amend this offer without notice. Offer expires 12/31/2023. For more information, visit our website www.genotropin.com, call 1-800-645-1280 or visit Pfizer.com. Genotropin Copay Program, PO Box 220746, Charlotte, NC 28222-0746Updated Pfizer Bridge Program provider portal Discover the support programs available to your patients  Visit PfizerBridgeProgram.com to:
  • Help patients enroll in the Pfizer Bridge Program
  • Conduct electronic Benefit Verifications
  • Prepare and submit electronic Prior Authorization requests
  • Provide e-signatures for GENOTROPIN prescriptions
  • Track patient's status and receive notifications
  • Access digital forms and resources
Devices PBP Services Brochure

Find out more about the Pfizer Bridge Program here

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To report an adverse event, please call 1-800-438-1985

Pfizer for Professionals 1-800-505-4426

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PP-GEN-USA-1185
INDICATIONS

Indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone (GH).

Indicated for the treatment of pediatric patients who have growth failure due to Prader-Willi syndrome (PWS). The diagnosis of PWS should be confirmed by appropriate genetic testing (see CONTRAINDICATIONS).

Indicated for the treatment of growth failure in children born small for gestational age (SGA) who fail to manifest catch-up growth by age 2 years.

Indicated for the treatment of growth failure associated with Turner syndrome (TS).

Indicated for the treatment of idiopathic short stature (ISS), also called non-growth hormone­deficient short stature, defined by height standard deviation score (SDS) ≤ -2.25, and associated with growth rates unlikely to permit attainment of adult height in the normal range, in pediatric patients whose epiphyses are not closed and for whom diagnostic evaluation excludes other causes associated with short stature that should be observed or treated by other means.

Indicated for growth hormone replacement therapy in adults with growth hormone deficiency (GHD) of either childhood- or adult-onset etiology. GHD should be confirmed as appropriate.

Please see full Prescribing Information for Genotropin.
Important Safety Information Somatropin should not be used for growth promotion in pediatric patients with closed epiphyses.

Somatropin is contraindicated in patients with active proliferative or severe nonproliferative diabetic retinopathy.

Somatropin is contraindicated in patients with active malignancy. Because growth hormone deficiency may be a sign of pituitary or other brain tumors, the presence of such tumors should be ruled out before treatment is initiated. Somatropin should not be used in patients with any evidence of progression or recurrence of an underlying intracranial tumor.

Somatropin in pharmacologic doses should not be used to treat patients with acute critical illness due to complications from open heart surgery, abdominal surgery or multiple accidental traumas, or those patients with acute respiratory failure due to an increased mortality. The safety of continuing replacement somatropin treatment for approved uses in patients who develop these illnesses has not been established. 

Somatropin is contraindicated in patients with Prader-Willi syndrome who are severely obese or have respiratory impairment.

GENOTROPIN is contraindicated in patients with a known hypersensitivity to somatropin or any of its excipients. Serious systemic hypersensitivity reactions including anaphylactic reactions and angioedema have been reported with postmarketing use of somatropin products. Patients and caregivers should be informed that such reactions are possible and that prompt medical attention should be sought if an allergic reaction occurs.

New-onset Type-2 diabetes mellitus has been reported. Monitor patients with glucose intolerance closely; dosage of antihyperglycemic drug may need to be adjusted. Monitor carefully if somatropin is administered in combination with glucocorticoid therapy and/or other drugs metabolized by the CP450 pathway.

In childhood cancer survivors, an increased risk of a second neoplasm, in particular meningiomas, has been reported in patients treated with somatropin after their first neoplasm, particularly those who were treated with cranial radiation. Children with certain rare genetic causes of short stature have an increased risk of developing malignancies. Practitioners should thoroughly consider the risks and benefits of starting somatropin in these patients and if treatment is initiated, should carefully monitor these patients for development of neoplasms. Patients should be monitored carefully for any malignant transformation of skin lesions.

Intracranial hypertension (IH) has been reported in a small number of patients treated with somatropin. If papilledema is observed during somatropin treatment, treatment should be stopped and reassessed. Patients with Turner syndrome and Prader-Willi syndrome may be at increased risk for the development of IH.

Undiagnosed/untreated hypothyroidism may prevent an optimal response to somatropin, in particular, the growth response in children. Patients with Turner syndrome have an inherently increased risk of developing autoimmune thyroid disease and primary hypothyroidism. In patients with growth hormone deficiency, central (secondary) hypothyroidism may first become evident or worsen during somatropin treatment. Therefore, patients treated with somatropin should have periodic thyroid function tests, and thyroid hormone replacement therapy should be initiated or appropriately adjusted when indicated.

Patients treated with somatropin who have or are at risk for pituitary hormone deficiency(s) may be at risk for reduced serum cortisol levels and/or unmasking central hypoadrenalism and should be monitored for reduced serum cortisol levels. In addition, patients treated with glucocorticoid replacement for pre-existing hypoadrenalism may require an increase in their maintenance or stress doses following initiation of somatropin treatment and should be monitored for reduced cortisol levels and/or need for glucocorticoid dose increases.

Progression of scoliosis can occur in patients who experience rapid growth. Patients with scoliosis should be monitored for manifestation or progression during somatropin therapy.

Slipped capital femoral epiphyses may occur more frequently in patients with endocrine disorders (including GHD and Turner syndrome) or in patients undergoing rapid growth. Any pediatric patient with the onset of a limp or complaints of hip or knee pain during somatropin therapy should be carefully evaluated.

Somatropin should be used during pregnancy only if clearly needed and with caution in nursing mothers because it is not known whether somatropin is excreted in human milk.

Subcutaneous injection of somatropin at the same site repeatedly may result in tissue atrophy. This can be avoided by rotating the injection site.

Cases of pancreatitis have been reported rarely in children and adults receiving somatropin treatment, with some evidence supporting a greater risk in children compared with adults. Published literature indicates that girls who have Turner syndrome may be at greater risk than other somatropin-treated children. Pancreatitis should be considered in any somatropin-treated patient, especially a child, who develops persistent severe abdominal pain.

In clinical trials with GENOTROPIN in pediatric GHD patients, the following events were reported infrequently: injection site reactions, including pain or burning associated with the injection, fibrosis, nodules, rash, inflammation, pigmentation, or bleeding; lipoatrophy; headache; hematuria; hypothyroidism; and mild hyperglycemia.

In clinical studies of 273 pediatric patients born SGA treated with GENOTROPIN, the following clinically significant events were reported: mild transient hyperglycemia; 1 patient with benign intracranial hypertension; 2 patients with central precocious puberty; 2 patients with jaw prominence; and several patients with aggravation of preexisting scoliosis, injection site reactions, and self-limited progression of pigmented nevi. Anti-hGH antibodies were not detected in any of the patients treated with GENOTROPIN.

Deaths have been reported with the use of a growth hormone in pediatric PWS patients with severe obesity, history of upper airway obstruction or sleep apnea, and/or unidentified respiratory infection. Therefore, all patients with PWS should be evaluated and monitored for signs of upper airway obstruction, sleep apnea, and respiratory infections, and have effective weight control.

In clinical trials with GENOTROPIN in pediatric patients with PWS, the following drug-related events were reported: edema, aggressiveness, arthralgia, benign intracranial hypertension, hair loss, headache, and myalgia.

Somatropin may increase the occurrence of otitis media in Turner syndrome patients. In 2 clinical studies with GENOTROPIN in pediatric patients with Turner syndrome, the most frequently reported adverse events were respiratory illnesses (influenza, tonsillitis, otitis, sinusitis), joint pain, and urinary tract infection. The only treatment-related adverse event that occurred in more than 1 patient was joint pain.

In 2 clinical studies with GENOTROPIN in pediatric patients with ISS, the most commonly encountered adverse events included upper respiratory tract infections, influenza, tonsillitis, nasopharyngitis, gastroenteritis, headaches, increased appetite, pyrexia, fracture, altered mood, and arthralgia.

In clinical trials with GENOTROPIN in adults with GHD, the majority of side effects were symptoms of fluid retention, including peripheral swelling/edema, arthralgia, pain and stiffness of the extremities, myalgia, paresthesia, and hypoesthesia. Generally, these were transient and dose-dependent.

In women on oral estrogen replacement, a larger dose of somatropin may be required to achieve the defined treatment goal.

Elderly patients may be more sensitive to the action of somatropin, and therefore may be more prone to develop adverse reactions.

The cartridges of GENOTROPIN contain m-Cresol and should not be used by patients with a known sensitivity to this preservative.

Subcutaneous injection of somatropin at the same site repeatedly may result in tissue atrophy. This can be avoided by rotating the injection site.

Health care providers should supervise the first injection and provide appropriate training and instruction for the proper use of all devices for GENOTROPIN.

Rx only IndicationsIndicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone (GH).

Indicated for the treatment of pediatric patients who have growth failure due to Prader-Willi syndrome (PWS). The diagnosis of PWS should be confirmed by appropriate genetic testing (see CONTRAINDICATIONS).

Indicated for the treatment of growth failure in children born small for gestational age (SGA) who fail to manifest catch-up growth by age 2 years.

Indicated for the treatment of growth failure associated with Turner syndrome (TS).

Indicated for the treatment of idiopathic short stature (ISS), also called non-growth hormone-deficient short stature, defined by height standard deviation score (SDS) ≤ -2.25, and associated with growth rates unlikely to permit attainment of adult height in the normal range, in pediatric patients whose epiphyses are not closed and for whom diagnostic evaluation excludes other causes associated with short stature that should be observed or treated by other means.

Indicated for growth hormone replacement therapy in adults with growth hormone deficiency (GHD) of either childhood- or adult-onset etiology. GHD should be confirmed as appropriate.

Please see full Prescribing Information.